Why is the cost of Russian IVF higher than the previous two generations?
The first generation of in vitro fertilization-embryo transfer (IVF-ET) is mainly used to treat female infertility patients, such as tubal obstruction, ovulation disorder, endometriosis and so on.
Second-generation test-tube infants, also known as intracytoplasmic sperm microinjection (ICSI), mainly treat male infertility, such as oligozoospermia, weakness and spermatozoa. Owing to the low density or vitality of sperm, it is impossible to fertilize the eggs naturally. Therefore, it is necessary to inject a sperm into the eggs by means of a single sperm microinjection system to fertilize them.
The third generation of test-tube infants, also known as pre-implantation embryo genetic diagnosis (PGD), refers to biopsy and genetic analysis of the embryos of patients with genetic risk during in vitro fertilization, so as to select embryos without genetic diseases to be implanted into uterine cavity, so as to obtain the diagnosis method of normal fetuses, which can effectively prevent children with genetic diseases. Birth.
Indications are as follows: 1. Monogenous hereditary diseases: autosomal recessive inheritance, B-globin production disorder anemia, fibrocystic degeneration; autosomal dominant inheritance diseases, such as a-globin production disorder anemia, X-chromosome associated inheritance, such as hemophilia.2, triplet multiple sequence abnormalities, such as fragile X-chromosome syndrome.3, chromosome number. Objectives and structural abnormalities: aneuploidy, balanced translocation and Robertson translocation.
The third generation of test-tube infants in Russia can produce cancer-free babies by using PGS Technology
PGS is preimplantation genetic screening. Before implantation, PGS is used to detect chromosome number and structural abnormalities of early embryos. The 23 pairs of chromosome structure and number of embryos are detected, and the genetic abnormalities of embryos are analyzed by comparison. The normal embryos are selected and implanted into uterus in order to obtain them. Normal pregnancy can improve clinical pregnancy rate and reduce multiple pregnancy.
PGD is a pre-implantation genetic diagnosis, which is mainly used to check whether the embryo carries genes with genetic defects. After the sperm-egg combination to form fertilized eggs and develop into embryos, PGD technology is used to detect genes before implantation into the uterus in order to avoid some genetic diseases for IVF test-tube babies. Diagnosis of diseases caused by single gene defects, such as hemophilia, thalassemia, etc., can be directly found through such diagnosis.
With so many high-tech technologies, compared with the first and second generation of IVF technology, the third generation of IVF in Russia is a sublimation in overall technology.